Mal-PEG-Vitamin D，马来酰亚胺PEG维生素D

Mal-PEG-Vitamin D，马来酰亚胺PEG维生素D

金畔生物  Laysan  Nanocs修饰性PEG

在生命科学领域，上海金畔生物为业界提供了丰富的实验室和生物医药生产研发的产品。在这里要感谢广大客户多年来对上海金畔生物科技有限公司的支持和厚爱，我们将一如既往的为广大客户带来Laysan、Nanocs等品牌的修饰性PEG高品质的产品和服务，欢迎广大新老客户来电咨询。

修饰性PEG

1 PEG化学结构及性质

1.1 PEG化学结构

结构式CH2（OH）-（CH2CH2O）n -CH2OH

1.2 PEG性质【1】

聚乙二醇系列产品通常情况下溶于水和多种有机溶剂，不溶于脂肪烃、苯、乙二醇等，不会水解变

质，有广泛的溶解范围和优良的相容性、很好的稳定性、润滑性、成膜性、增塑性、分散性等。系低毒物质，且无刺激性，属非离子型聚合物。

2 聚乙二醇修饰剂

根据化学修饰剂与蛋白质之间反应性质的不同，修饰反应主要分为酰化反应、烷基化反应、氧化还原反应、芳香环取代反应等类型，对蛋白质进行氨基、巯基和羧基等侧链基团进行化学修饰。根据被修饰化合物包括蛋白质、多肽、单克隆抗体分子片段、以及小分子化合物等的不同分子量大小、分子结构以及其理化特性，公司采取不同的聚乙二醇化技术方法对这些化合物进行修饰【2,3】。

Nanocs–Vitamin D PEG Mal马来酰亚胺PEG维生素D

PG2-MLVD-5k Vitamin D PEG Maleimide 5000 Da 10 mg $385.00
PG2-MLVD-3k Vitamin D PEG Maleimide 3400 Da 10 mg $425.00
PG2-MLVD-2k Vitamin D PEG Maleimide 2000 Da 10 mg $425.00

Description:

Vitamin D PEG derivatives are a class of bioactive PEGs that can be used to for drug delivery or bioassay development. Nanocs can provide both 2 and 3 hydroxyl Vitamin D PEG derivatives.

Physical Properties:

White solid or viscous liquid depends on molecule weight;

Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Mal-PEG -ACRL，马来酰亚胺PEG丙烯酸脂

ACRL- PEG Mal，马来酰亚胺PEG丙烯酸脂，丙烯酸聚乙二醇马来酰亚胺

金畔生物、Laysan Bio、  Nanocs修饰性PEG

在生命科学领域，上海金畔生物为业界提供了丰富的实验室和生物医药生产研发的产品。在这里要感谢广大客户多年来对上海金畔生物科技有限公司的支持和厚爱，我们将一如既往的为广大客户带来Laysan、Nanocs等品牌的修饰性PEG高品质的产品和服务，欢迎广大新老客户来电咨询。

PEG的修饰作用

摘要：聚乙二醇修饰即PEG化，是将活化的PEG通过化学方法以共价键偶联到蛋白质或多肽分子上。自Davis1977年首次用PEG 修饰牛血清白蛋白以来，PEG修饰技术广泛应用于多种蛋白质和多肽的化学修饰，多个PEG修饰药物上市或在临床研究中。 PEG修饰具有半衰期延长、免疫原性降低或消失、毒副作用减少以及物理、化学和生物稳定性增强等。

关键词:PEG(聚乙二醇)；修饰PEG

高分子聚乙二醇（PEG）由于其毒性小、无抗原性、具有良好的两亲性，且生物相容性已获FDA认可，对蛋白质的改造具有无可取代的优势。聚乙二醇化修饰技术通过共价键，将聚乙二醇与被修饰药物耦联，改善药物的理化性质和生物学活性，这种技术现已广泛应用于蛋白质(肽类)、酶、抗体及小分子药物。

Nanocs–ACRL- PEG Mal 马来酰亚胺PEG丙烯酸脂，丙烯酸聚乙二醇马来酰亚胺

PG2-ARML-5k Acrylate PEG Maleimide 5000 Da 100 mg $385.00
PG2-ARML-3k Acrylate PEG Maleimide 3400 Da 100 mg $425.00
CAT. NO. PRODUCT NAME SPECIFICATION SIZE PRICE
PG2-ARML-2k Acrylate PEG Maleimide 2000 Da 100 mg $425.00

Description:Aacrylate functionalized PEG derivatives can be used to make hydrogel via radical polymerization process. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. .Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C, dessiccated Protect from light. Avoid frequent thaw and freeze.

Laysan马来酰亚胺MAL-PEG

Laysan bio马来酰亚胺PEG,MAL-PEG,马来酰亚胺聚乙二醇

Laysan修饰性PEG    Laysan聚乙二醇     Laysan bio修饰性PEG

Laysan Bio, Inc.是一家生物技术公司，为客户提供用于各种研发平台的新型聚合物。Laysan为学院，研究中心，生物技术和制药研发公司提供目录，定制和标准的活性聚（乙二醇）试剂。Laysan销售各种的活性聚合物，并提供快速响应的客户服务和技术支持。

在生命科学领域，上海金畔生物为业界提供了丰富的实验室和生物医药生产研发的产品。在这里要感谢广大客户多年来对上海金畔生物科技有限公司的支持和厚爱，我们将一如既往的为广大客户带来Laysan、Nanocs等品牌的修饰性PEG高品质的产品和服务，欢迎广大新老客户来电咨询。

Monofunctional  单官能团修饰性PEG
mPEG-Maleimide (MAL), MW 2,000    甲氧基聚乙二醇马来酰亚胺，马来酰亚胺PEG甲氧基

mPEG-Maleimide, MW 2,000 – 1 gram   Item# mPEG-MAL-2000-1g    $140.00

mPEG-Maleimide (MAL), MW 5,000

mPEG-Maleimide, MW 5,000 – 1 gram   Item# MPEG-MAL-5000-1g   $140.00

mPEG-Maleimide, MW 5,000 – 5 gram   Item# MPEG-MAL-5000-5g    $560.00

mPEG-Maleimide (MAL), MW 10,000

mPEG-Maleimide, MW 10kDa – 1 gram   Item# MPEG-MAL-10K-1g    $140.00

mPEG-Maleimide, MW 10kDa – 5 gram  Item# MPEG-MAL-10K-5g    $560.00

mPEG-Maleimide (MAL), MW 20,000

mPEG-Maleimide, MW 20kDa – 1 gram   Item# MPEG-MAL-20K-1g   $140.00

mPEG-Maleimide, MW 20kDa – 5 gram  Item# MPEG-MAL-20K-5g    $560.00

mPEG-Maleimide (MAL), MW 30,000

mPEG-Maleimide, MW 30kDa – 1 gram  Item# MPEG-MAL-30K-1g    $150.00

mPEG-Maleimide, MW 30kDa – 5 gram   Item# MPEG-MAL-30K-5g   $600.00

mPEG-Maleimide (MAL), MW 1,000

mPEG-Maleimide, MW 1,000 – 1 gram   Item# mPEG-MAL-1000-1g    $200.00

Kits      甲氧基聚乙二醇马来酰亚胺，马来酰亚胺PEG甲氧基 套装
mPEG-Maleimide Kit (mPEG-MAL)   4 molecular weights in kit (2K, 5K, 10K, 20K)

mPEG-Maleimide, 4MW Kit   Item# MPEG-MAL-4MW Kit    $140.00

This product contains 4 bottles with 100 mg in each bottle at molecular weights of 2,000, 5,000, 10,000, and 20,000.

Bifunctional   同双官能团修饰性PEG 
Maleimide-PEG-Maleimide (MAL-PEG-MAL), MW 3,400    马来酰亚胺PEG马来酰亚胺，马来酰亚胺聚乙二醇马来酰亚胺，双端马来酰亚胺PEG

Maleimide-PEG-Maleimide, MW 3,400 – 1 gram  Item# MAL-PEG-MAL-3400-1g   $160.00

Maleimide-PEG-Maleimide, MW 3,400 – 5 gram  Item# MAL-PEG-MAL-3400-5g   $640.00

Maleimide-PEG-Maleimide (MAL-PEG-MAL), MW 1,000
Maleimide-PEG-Maleimide (MAL-PEG-MAL), MW 2,000

Maleimide-PEG-Maleimide, MW 2,000 – 1 gram   Item# MAL-PEG-MAL-2K-1g   $200.00

Maleimide-PEG-Maleimide (MAL-PEG-MAL), MW 5,000

Maleimide-PEG-Maleimide, MW 5,000 – 1 gram    Item# MAL-PEG-MAL-5K-1g    $160.00

Maleimide-PEG-Maleimide (MAL-PEG-MAL), MW 10,000

Maleimide-PEG-Maleimide, MW 10kDa – 1 gram   Item# MAL-PEG-MAL-10K-1g    $180.00

Heterobifunctional   异双官能团修饰性PEG
Biotin-PEG-Maleimide, MW 3,400   生物素PEG马来酰亚胺,马来酰亚胺聚乙二醇生物素

Biotin-PEG-Maleimide, MW 3,400 – 100 mg   Item# Biotin-PEG-MAL-3400-100mg    $280.00

Biotin-PEG-Maleimide, MW 3,400 – 1 gram   Item# Biotin-PEG-MAL-3400-1g   $600.00

Biotin-PEG-Maleimide, MW 3,400 – 500 mg   Item# Biotin-PEG-MAL-3400-500mg   $360.00

Biotin-PEG-Maleimide, MW 5,000

Biotin-PEG-Maleimide, MW 5,000 – 1 gram   Item# Biotin-PEG-MAL-5000-1g   $600.00
Biotin-PEG-Maleimide, MW 5,000 – 100 mg    Item# Biotin-PEG-MAL-5K-100mg     $280.00

Biotin-PEG-Maleimide, MW 5,000 – 500 mg    Item# Biotin-PEG-MAL-5K-500mg     $360.00

Biotin-PEG-Maleimide, MW 10,000

Biotin-PEG-Maleimide, MW 10,000 – 1 gram    Item# Biotin-PEG-MAL-10K-1g     $600.00

Biotin-PEG-Maleimide, MW 10,000 – 100 mg   Item# Biotin-PEG-MAL-10K-100mg     $280.00

Biotin-PEG-Maleimide, MW 10,000 – 500 mg    Item# Biotin-PEG-MAL-10K-500mg   $360.00

DSPE-PEG-Maleimide, MW 3,400  马来酰亚胺PEG磷脂，磷脂聚乙二醇马来酰亚胺

DSPE-PEG-Maleimide, MW 3,400 – 500 mg   Item# DSPE-PEG-MAL-3400-500mg     $300.00

DSPE-PEG-Maleimide, MW 3,400 – 1 gram  Item# DSPE-PEG-MAL-3400-1g   $500.00

DSPE-PEG-Maleimide, MW 3,400 – 5 gram   Item# DSPE-PEG-MAL-3400-5g    $2,000.00

DSPE-PEG-Maleimide, MW 2,000

DSPE-PEG-Maleimide, MW 2,000 – 1 gram   Item# DSPE-PEG-MAL-2000-1g  $500.00

DSPE-PEG-Maleimide, MW 2,000 – 500 mg   Item# DSPE-PEG-MAL-2000-500mg     $300.00

HO-PEG-Maleimide, MW 3,400   马来酰亚胺PEG羟基，羟基聚乙二醇马来酰亚胺

HO-PEG-MAL, MW 3,400 – 1 gram   Item# HO-PEG-MAL-3400-1g   $330.00

HO-PEG-MAL, MW 3,400 – 5 gram   Item# HO-PEG-MAL-3400-5g   $1,320.00

HO-PEG-MAL, MW 3,400 – 500 mg    Item# HO-PEG-MAL-3400-500mg    $210.00

HO-PEG-Maleimide, MW 2,000

HO-PEG-MAL, MW 2,000 – 1 gram   Item# HO-PEG-MAL-2000-1g      $330.00

HO-PEG-MAL, MW 2,000 – 500 mg   Item# HO-PEG-MAL-2000-500mg     $210.00

HO-PEG-Maleimide, MW 5,000

HO-PEG-MAL, MW 5,000 – 1 gram   Item# HO-PEG-MAL-5000-1g    $330.00

HO-PEG-MAL, MW 5,000 – 500 mg   Item# HO-PEG-MAL-5000-500mg     $210.00

Maleimide-PEG-SVA, MW 3,400   马来酰亚胺PEG琥珀酰亚胺戊酸酯,琥珀酰亚胺戊酸酯聚乙二醇马来酰亚胺

Maleimide-PEG-Succinimidyl Valerate, MW 3,400 – 100 mg   Item# MAL-PEG-SVA-3400-100mg     $210.00

Maleimide-PEG-Succinimidyl Valerate, MW 3,400 – 500 mg   Item# MAL-PEG-SVA-3400-500mg    $300.00

Maleimide-PEG-Succinimidyl Valerate, MW 3,400 – 1 gram   Item# MAL-PEG-SVA-3400-1gram   $500.00

Maleimide-PEG-SVA, MW 5,000

Maleimide-PEG-Succinimidyl Valerate, MW 5,000 – 100 mg    Item# MAL-PEG-SVA-5000-100mg     $210.00

Maleimide-PEG-Succinimidyl Valerate, MW 5,000 – 500 mg    Item# MAL-PEG-SVA-5000-500mg    $300.00

Maleimide-PEG-SVA, MW 2,000

Maleimide-PEG-Succinimidyl Valerate, MW 2,000 – 1 gram   Item# MAL-PEG-SVA-2000-1gram     $500.00

Maleimide-PEG-Succinimidyl Valerate, MW 2,000 – 100 mg    Item# MAL-PEG-SVA-2000-100mg    $210.00

Maleimide-PEG-Succinimidyl Valerate, MW 2,000 – 500 mg   Item# MAL-PEG-SVA-2000-500mg   $300.00

Maleimide-PEG-SVA, MW 10,000

Maleimide-PEG-Succinimidyl Valerate, MW 10kDa – 100 mg    Item# MAL-PEG-SVA-10K-100mg    $210.00

Maleimide-PEG-Succinimidyl Valerate, MW 10kDa – 500 mg   Item# MAL-PEG-SVA-10K-500mg    $300.00

Maleimide-PEG-SVA, MW 20,000

Maleimide-PEG-Succinimidyl Valerate, MW 20kDa – 100 mg   Item# MAL-PEG-SVA-20K-100mg     $210.00

Maleimide-PEG-Succinimidyl Valerate, MW 20kDa – 500 mg   Item# MAL-PEG-SVA-20K-500mg    $300.00


Acrylate-PEG-Maleimide, MW 3,400   丙烯酸PEG马来酰亚胺，马来酰亚胺聚乙二醇丙烯酸

Acrylate-PEG-Maleimide, MW 3,400 – 1 gram   Item# ACRL-PEG-MAL-3400-1g   $500.00

Acrylate-PEG-Maleimide, MW 3,400 – 500 mg   Item# ACRL-PEG-MAL-3400-500mg    $350.00

Acrylate-PEG-Maleimide, MW 5,000

Acrylate-PEG-Maleimide, MW 5,000 – 1 gram    Item# ACRL-PEG-MAL-5000-1g   $500.00

Acrylate-PEG-Maleimide, MW 5,000 – 500 mg   Item# ACRL-PEG-MAL-5000-500mg   $350.00

Multi-arm   多臂马来酰亚胺修饰性PEG
4 arm PEG-Maleimide (MAL), MW 20,000   四臂PEG马来酰亚胺，四臂马来酰亚胺聚乙二醇

4arm-PEG-MAL, MW 20kDa – 1 gram   Item# 4arm-PEG-MAL-20K-1g    $160.00 

4arm-PEG-MAL, MW 20kDa – 5 gram   Item# 4arm-PEG-MAL-20K-5g   $640.00

4 arm PEG-Maleimide (MAL), MW 10,000

4arm-PEG-MAL, MW 10kDa – 1 gram   Item# 4arm-PEG-MAL-10K-1g   $160.00

4arm-PEG-MAL, MW 10kDa – 5 gram   Item# 4arm-PEG-MAL-10K-5g    $640.00

Nanocs Mal-PEG 马来酰亚胺PEG

Nanocs Mal-PEG，马来酰亚胺PEG，马来酰亚胺聚乙二醇，Maleimide PEG

金畔生物  Laysan  Nanocs修饰性PEG

在生命科学领域，上海金畔生物为业界提供了丰富的实验室和生物医药生产研发的产品。在这里要感谢广大客户多年来对上海金畔生物科技有限公司的支持和厚爱，我们将一如既往的为广大客户带来Laysan、Nanocs等品牌的修饰性PEG高品质的产品和服务，欢迎广大新老客户来电咨询。

Mal-PEG，马来酰亚胺PEG，马来酰亚胺聚乙二醇，Maleimide PEG

Cat. No. Product Name Specification Size Price
PG2-ML-5k Maleimide PEG Maleimide, MAL-PEG-MAL 5000 Da 100 mg $185.00
PG2-ML-3k Maleimide PEG Maleimide, MAL-PEG-MAL 3400 Da 100 mg $245.00
PG2-ML-2k Maleimide PEG Maleimide, MAL-PEG-MAL 2000 Da 100 mg $285.00
PG2-ML-10k Maleimide PEG Maleimide, MAL-PEG-MAL 10000 Da 100 mg $325.00
PG2-ML-1k Maleimide PEG Maleimide, MAL-PEG-MAL 1000 Da 100 mg $325.00
PG2-ML-400 Maleimide PEG Maleimide, MAL-PEG-MAL 400 Da 100 mg $285.00
PG2-ML-600 Maleimide PEG Maleimide, MAL-PEG-MAL 600 Da 100 mg $285.00
PG2-ML-20k Maleimide PEG Maleimide, MAL-PEG-MAL 20000 Da 100 mg $385.00
PG2-ML-35k Maleimide PEG Maleimide, MAL-PEG-MAL 35000 Da 100 mg $385.00
PG2-MLNS-5k-1 Maleimide PEG NHS, MAL-PEG-NHS 5000 Da 100 mg $245.00
PG2-MLNS-5k-2 Maleimide PEG NHS, MAL-PEG-NHS 5000 Da 500 mg $980.00
PG2-MLNS-3k Maleimide PEG NHS, MAL-PEG-NHS 3400 Da 100 mg $285.00
PG2-MLNS-2k Maleimide PEG NHS, MAL-PEG-NHS 2000 Da 100 mg $325.00
PG2-MLNS-10k Maleimide PEG NHS, MAL-PEG-NHS 10000 Da 100 mg $385.00
PG2-MLNS-1k Maleimide PEG NHS, MAL-PEG-NHS 1000 Da 100 mg $385.00
PG2-MLNS-20k Maleimide PEG NHS, MAL-PEG-NHS 20000 Da 100 mg $385.00
PG2-AMML-5k Maleimide PEG Amine, MAL-PEG-NH2 5000 Da 100 mg $245.00
PG2-AMML-3k Maleimide PEG Amine, MAL-PEG-NH2 3400 Da 100 mg $285.00
PG2-AMML-2k Maleimide PEG Amine, MAL-PEG-NH2 2000 Da 100 mg $325.00
PG2-AMML-10k Maleimide PEG Amine, MAL-PEG-NH2 10000 Da 100 mg $385.00
PG2-AMML-1k Maleimide PEG Amine, MAL-PEG-NH2 1000 Da 100 mg $385.00
PG2-AMML-600 Maleimide PEG Amine, MAL-PEG-NH2 600 Da 100 mg $385.00
PG2-AMML-400 Maleimide PEG Amine, MAL-PEG-NH2 400 Da 100 mg $425.00
PG2-AMML-20k Maleimide PEG Amine, MAL-PEG-NH2 20000 Da 100 mg $425.00
PG2-CAML-5k Maleimide PEG Acid, MAL-PEG-COOH 5000 Da 100 mg $245.00
PG2-CAML-3k Maleimide PEG Acid, MAL-PEG-COOH 3400 Da 100 mg $285.00
PG2-CAML-2k Maleimide PEG Acid, MAL-PEG-COOH 2000 Da 100 mg $325.00
PG2-CAML-10k Maleimide PEG Acid, MAL-PEG-COOH 10000 Da 100 mg $385.00
PG2-CAML-1k Maleimide PEG Acid, MAL-PEG-COOH 1000 Da 100 mg $385.00
PG2-CAML-600 Maleimide PEG Acid, MAL-PEG-COOH 600 Da 100 mg $425.00
PG2-CAML-400 Maleimide PEG Acid, MAL-PEG-COOH 400 Da 100 mg $485.00
PG2-CAML-20k Maleimide PEG Acid, MAL-PEG-COOH 20000 Da 100 mg $485.00
PG2-MLPF-5k-1 Maleimide PEG PFP, MAL-PEG-PFP 5000 Da 25 mg $285.00
PG2-MLPF-3k Maleimide PEG PFP, MAL-PEG-PFP 3400 Da 25 mg $325.00
PG2-MLPF-2k Maleimide PEG PFP, MAL-PEG-PFP 2000 Da 25 mg $325.00
PG2-MLPF-10k Maleimide PEG PFP, MAL-PEG-PFP 10000 Da 25 mg $385.00
PG2-MLPF-1k Maleimide PEG PFP, MAL-PEG-PFP 1000 Da 25 mg $385.00
PG2-MLPF-20k Maleimide PEG PFP, MAL-PEG-PFP 20000 Da 25 mg $385.00